A recently published paper from Australian researchers in Victoria has looked at the question of immune effects measured in 29 children aged 5 to 11 years at 1 month and in 8 children up to 6 months post 2 Pfizer vaccinations as part of a larger study and summarises its findings by saying ' BNT162b2 vaccination in children alters cytokine responses to heterologous stimulants, particularly one month after vaccination'.
There are significant implications of this study.
The BNT vaccination did induce anti- spike and anti-Receptor Binding Domain ( anti RBD) Ig G antibodies, demonstrated in this study at 1 month and persisting to 6 months post vaccination, indicating a Th2 immune system 'humoral' and ' adaptive' response, together with increased cytokine responses on exposure to spike protein or the whole Covid virus tested. This should equate to enhanced immunity against Covid and the spike protein if normal mucosal immunity is maintained.
However this study also clearly demonstrated that the cytokines (or cell messenger molecules) required for the initial response of the innate, cell-mediated immunity prior to antibody formation, to numerous tested viruses and bacteria, were dramatically decreased after 1 month. Interferon gamma, the key messenger to activate the first arm of the immune system which lives in the mucosal tissues lining our airways and gut, was reduced some tenfold, as was
MCP-1, a protein which attracts monocytes into tissues, another key player in innate cellular immunity. The immune system, simplified, has 2 arms: innate and adaptive. The innate immune system lines the mucosal barriers of the respiratory and gut particularly, is the first and major barrier to any and all infections and is predominantly mediated by immune cell actions. This is also called TH1 immunity.It is only after an infectious agent has traversed the mucosal barrier that specific antibodies – the adaptive immunity – are made. This is often called TH2 immunity. This study made it very apparent that while the Covid vaccine induces anti spike antibodies, it markedly reduces initial protective responses to many other viral and bacterial infections as measured at 1 month post vaccination, with persistent reductions in antiviral protection to 6 months. A similar effect has also recently been shown in adults. This same mechanism of action likely occurs with all other injectable vaccinations.
The bigger question of how this is altering overall immune function is gradually being acknowledged: 'Our results add to the evolving evidence that SARS-CoV-2 mRNA vaccination reprograms both adaptive and innate immune responses.' Our immune systems are being 'reprogrammed', like a faulty computer programme needing to be rewritten or upgraded. Although not acknowledged in the abstract conclusion, the authors state that ' Our findings suggest SARS-CoV-2 mRNA vaccination could alter the immune response to other pathogens, which cause both vaccine-preventable and non-vaccine-preventable diseases . This is particularly relevant in children', and 'That SARS-CoV-2 mRNA vaccination in children could impact immune responses to other pathogens emphasises the need for further research and consideration of heterologous effects in vaccination policies given their broad public health implications.' They acknowledge there is a potential issue here. Perhaps this is behind the surge in Streptococcal infections in children being noted worldwide?
For our children to be healthy, they need a well -functioning innate immune system lining the gut and respiratory mucosa, first and foremost. This does not need reprogramming but support. This does not come by vaccination.